A 17-year-old youth was shot on the Wendlesworth Estate in Wandsworth on Thursday night.
Police were called at 8pm to Vermont Road, where they found the injured teenager but were unable to make arrests.
The youth was taken to a south London hospital in a serious but stable condition.
Detectives from Operation Trident are now investigating the incident.
No further details have been released.
This is just the latest incident in a month-long spate of knife and gun violence in the borough.
Anyone with information should call Crimestoppers on 0800 555 111.
Do you know more? Call our newsdesk on 0208 330 9537.
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